Search results for "energetic homeostasis"

Hypothalamic glucose sensing : mitochondrial dynamic involument in reactive oxygen species signaling

2011

Energetic homeostasis results in the balance between energy intake and expenditure. The hypothalamus plays an important role in the regulation of both energetic metabolism and food intake in sensing hormonal and metabolic signals. For instance, changes in hypothalamic glucose level modulate food intake and insulin secretion. We have previously found that 1) increased hypothalamic glucose level triggers production of mitochondrial reactive oxygen species (mROS) from the electron transport chain; 2) hypothalamic mROS production is involved in glucose homeostasis and food intake control. The molecular mechanisms involved in glucose-induced hypothalamic mROS production are still unknown. Mitoch…

Détection hypothalamique de l’hyperglycémie : rôle de la dynamique mitochondriale dans la signalisation par les espèces actives de l’oxygène

2011